CVG Journal Club

Presentations 2008-2009

DATE PRESENTATION
May 28, 2009
4:00-5:00 pm
George A. Garinis, Lieneke M. Uittenboogaard, Heike Stachelscheid, Maria Fousteri, Wilfred van Ijcken, Timo M. Breit, Harry van Steeg, Leon H. F. Mullenders, Gijsbertus T. J. van der Horst, Jens C. Brüning, Carien M. Niessen, Jan H. J. Hoeijmakers and Björn Schumacher. (2009). Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity. Nat. Cell Biol. 11:604-615.
April 30, 2009
4:00-5:00 pm
Fischer J, Koch L, Emmerling C, Vierkotten J, Peters T, Brüning JC, Rüther U. Inactivation of the Fto gene protects from obesity. Nature. 2009 Apr 16;458(7240):894-8.
March 26, 2009
4:00-5:00 pm
Pollard KS, Salama SR, Lambert N, Lambot MA, Coppens S, Pedersen JS, Katzman S, King B, Onodera C, Siepel A, Kern AD, Dehay C, Igel H, Ares M Jr, Vanderhaeghen P, Haussler D. An RNA gene expressed during cortical development evolved rapidly in humans. Nature. 443, 167-172. (14 September 2006).
February 26, 2009
4:00-5:00 pm
Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells; Bo Wen, Hao Wu, Yoichi Shinkai, Rafael A Irizarry & Andrew P Feinberg; Nature Genetics Vol 41, No 2, Feb 2009
January 29, 2009
4:00-5:00 pm
Ondrej Mihola et al, A Mouse Speciation Gene Encodes a Meiotic Histone H3 Methyltransferase; Science 323, 373 (2009)
November 20, 2008
4:00-5:00 pm
Guillaume Bourque et al, Evolution of the mammalian transcription factor binding repertoire via transposable elements. Genome Res. November 2008 18:1752-1762;
October 30, 2008
4:00-5:00 pm
Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1 Ann-Hwee Lee, Erez F. Scapa, David E. Cohen, Laurie H. Glimcher Science 13 June 2008: Vol. 320. no. 5882, pp. 1492 - 1496
September 18, 2008
4:00-5:00 pm
Wang T, Zeng J, Lowe CB, Sellers RG, Salama SR, Yang M, Burgess SM, Brachmann RK, Haussler D. Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53. Proc. Natl Acad. Sci. USA (2007) 104:18613–18618.

Presentations 2007-2008

DATE PRESENTATION
May 29, 2008
4:00-5:00 pm
Sequential Expression of Pluripotency Markers during Direct Reprogramming ofMouse Somatic Cells; Brambrink et.al. Cell Stem Cell Volume 2, Issue 2, 7 February 2008, Pages 151-159
April 24, 2008
4:00-5:00 pm
A Mouse Model of Mitochondrial Disease Reveals Germline Selection Against Severe mtDNA Mutations. Weiwei Fan, et. al. Science 15 February 2008: Vol. 319. no. 5865, pp. 958 - 962
March 27, 2008
4:00-5:00 pm
The genomic landscapes of human breast and colorectal cancers. Wood LD, et.al. Science. 2007 Nov 16;318(5853):1108-13.
February 28, 2008
4:00-5:00 pm
Genome-wide network of regulatory genes for construction of a chordate embryo. Shoguchi E, Hamaguchi M, Satoh N. Dev Biol. 2008 Jan 26
January 31, 2008
4:00-5:00 pm
Drosophila 12 Genomes Consortium. 2007. Evolution of genes and genomes on the Drosophila phylogeny. Nature 450:203-218.
November 29, 2007
4:00-5:00 pm
Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions; France Denoeud, et. al.; Genome Research 2007 17:746-759
October 25, 2007
4:00-5:00 pm
Heat Shock Factor 1 Is a Powerful Multifaceted Modifier of Carcinogenesis; Chengkai Dai, Luke Whitesell, Arlin B. Rogers and Susan Lindquist; Cell Volume 130, Issue 6, 21 September 2007, Pages 1005-1018
September 27, 2007
4:00-5:00 pm
Bernstein BE, et al. A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells. (2006) Cell 125, 315-326.
August 30, 2007
4:00-5:00 pm
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney.
PNAS | November 21, 2006 | vol. 103 | no. 47 | 17985-17990

Presentations 2006-2007

DATE PRESENTATION
April 26, 2007
4:00-5:00 pm
A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445, 881-885 (22 February 2007)
March 29, 2007
4:00-5:00 pm
Genome-wide prediction of imprinted murine genes. Philippe P. Luedi,Alexander J. Hartemink, and Randy L. Jirtle. Genome Res. 15:875-884, 2005.
February 22, 2007
4:00-5:00 pm
"Transcriptional profiling of aging in human muscle reveals a common aging signature" Jacob M. Zahn1, Rebecca Sonu1, Hannes Vogel, Emily Crane1, Krystyna Mazan-Mamczarz, Ralph Rabkin, Ronald W. Davis, Kevin G. Becker, Art B. Owen, Stuart K. Kim.
January 25, 2007
4:00-5:00 pm
L.J. Niedernhofer et al., "A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis," Nature, 444:1038 - 43, 21/28 December 2006.
November 30, 2006
4:00-5:00 pm
"Analysis of one million base pairs of Neanderthal DNA" Green et al, Nature 444, 330-336 (16 November 2006)
and
"Sequencing and Analysis of Neanderthal Genomic DNA" Noonan et al. Science 17 November 2006: Vol. 314. no. 5802, pp. 1113 - 1118
October 26, 2006
4:00-5:00 pm
Sperm Chromatin Proteomics Identifies Evolutionarily Conserved Fertility Factors.
Diana S. Chu, Hongbin Liu, Paola Nix, Tammy F. Wu, Edward J. Ralston, John R. Yates III and Barbara J.Meyer.
Nature. 2006 Sep 7;443(7107):101-5
August 24, 2006
4:00-5:00 pm
Interchromosomal Interactions and Olfactory Receptor Choice
Authors: Stravos Lomvardas, Gilad Barnea, David Pisapia, Monica Mendelsohn, Jennifer Kirkland, and Richard Axel.
Cell 126, 403-413 July 28, 2006
September 28, 2006
4:00-5:00 pm
Evidence that DNA (Cytosine-5) Methyltransferase Regulates Synaptic Plasticity in the Himpocampus
JM Levenson, TL Roth, FD Lubin, CA Miller, I Huang, P Desal, LM Malone, and JD Sweatt
J. Biol. Chem., Vol. 281, Issue 23, 15763-15773, June 9, 2006

Presentations 2005-2006

DATE PRESENTATION
May 25, 2006
4:00-5:00 pm
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells" Loh et al. Nature Genetics. 2006 Apr;38(4):431-40.
April 27, 2006
4:00-5:00 pm
The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development; Eran Hornstein, Jennifer H. Mansfield, Soraya Yekta, Jimmy Kuang-Hsien Hu, Brian D. Harfe, Michael T. McManus, Scott Baskerville, David P. Bartel & Clifford J. Tabin
March 23, 2006
4:00-5:00 pm
SNP technologies and human/dog/mouse HapMap issues and technology to use for LD mapping
February 23, 2006
4:00-5:00 pm
Lamason et al. (2005). SLC24A5, a Putative Cation Exchanger, Affects Pigmentation in Zebrafish and Humans. Science. 310: 1782-1786
January 26, 2006
4:00-5:00 pm
Mankad, et al. Natural gene therapy in monozygotic twins with Fanconi anemia.
December 1, 2005
4:00-5:00 pm
Rens W., et al.Resolution and evolution of the duck-billed platypus karyotype with an X1Y1X2Y2X3Y3X4Y4X5Y5 male sex chromosome constitution. Proc Natl Acad Sci U S A. 2004 Nov 16;101(46):16257-61.
October 27, 2005
4:00-5:00 pm
Fraga, M. F. et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc. Natl Acad. Sci. 102, 10604−10609 (2005)
September 29, 2005
4:00-5:00 pm
First Meeting
Serum response factor regulates a muscle Specific microRNA that targets Hand2 during cardiogenesis. Zhao et al. Nature. 436:14July2005;214-220.