Vertebrate Genomics Club, a.k.a "The Verge"

Presentations 2012-2013

DATE PRESENTERS
May 14, 2013 Wee Ming Yeo (Stokol Lab)
Fishing With Herpes
Yves Boisclair
The periparturient dairy cow as a model to study metabolic adaptations.
April 9, 2013
* 12:20 PM *
Special Guest: Dr. Adam Bogdanove
An introduction to TALENs, and now CRISPR/Cas9, for genome editing.
March 12, 2013 Ronald Harris-Warrick
Roles of identified interneurons in the networks controlling locomotion in the mouse spinal cord.
Jason Mezey
Bioinformatics, mapping, and network analysis methods for disease risk factor discovery
February 12, 2013 Patricia Cassano
Genomic Studies of Lung and Nutritional Phenotypes
Tim Cowley (Lee Lab)
Transcriptional co-regulator HCF1 is important for beta-cell function.
January 08, 2013 J. Thomas Brenna
Polyunsaturated Fatty Acid Desaturase (FADS) Genes. Novel Activities and Alternative Splicing
Rory Todhunter
GWAS reveals cathepsin L may have a role in early hip osteoarthritis.
December 11, 2012 Douglas Antczak
Host genetic factors influencing papillomavirus-induced cancer.
Scott Coonrod
Role for PADI2-catalyzed histone citrullination in estrogen signaling and cancer.
November 13, 2012 Brooke Wilson (Fortier Lab)
Identification of the Optimal Biologic to Enhance Endogenous Stem Cell Recruitment and Homing for Facilitated Musculoskeletal Tissue Regeneration.
Ned Place
A failure to replicate leads to mining microarray data for unintended purposes.
October 9, 2012 Paula Cohen
Integration of crossover pathways during mammalian meiosis.
Adam Boyko
Loss of PRDM9 leads to a unique recombination landscape in dogs.
September 11, 2012 Denis Duboule, University of Geneva
Hox genes regulation during development.

Presentations 2011-2012

DATE PRESENTERS
May 8, 2012 Kimberly O'Brien
Placental /Fetal utilization of heme and non-heme iron
Shu-Bing Qian
Translational Control in Gene Expression: from Nutrients to Ribosome
April 10, 2012 Susan Suarez
Intimacy: Mammalian sperm interactions with the oviduct.
Alexander Travis
Lipid regulation of sperm calcium transients and acrosome exocytosis: key roles for GM1 and the a1E subunit.
March 13, 2012 Andrew Bass
Shared Evolutionary Developmental Origins for Neural Basis of Vocal and Gestural Signaling
Jeremy Searle
Origins and Impacts of Natural Chromosomal Variation in the Mouse
February 14, 2012 Zhenglong Gu
Regulatory Changes in Metabolic Adaptation.
Adam Siepel
Bayesian inference of ancient human demography from individual genome sequences.
January 10, 2012 Findley Ransler (Harrison Lab, collaborating with Adkins-Regan Lab)
Rapid evolution of genes encoding a unique reproductive proteome in Japanese quail.
Morten Christiansen
Common Genetic Variants in FOXP2 are Associated with Individual Differences in Language and Sequential Learning.
December 13, 2011 Marcus Smolka
Orchestration of the DNA damage response by checkpoint kinases
Haiyuan Yu
Revealing molecular mechanisms of human disease genes through interactome analysis
November 8, 2011 Natasza Kurpios
The Exquisite Dorsal Mesentery Directs Left-Right Gut Morphogenesis
Vimal Selveraj
Translocator Protein and Mitochondrial Cholesterol Trafficking
October 11, 2011 Christopher Blackwood (Lin Lab)
Regulation of Neurogenesis by Jagged1 in the Embryonic Subventricular Zone.
Joyce Huan Chen (Shen Lab)
Chemokine mediated colon cancer metastasis.
September 13, 2011 Erin Wissink (Grimson Lab)
Experimentally identifying novel post-transcriptional cis-regulatory elements.
Ali Raza Awan (Pleiss Lab)
Profiling Splicing via a Novel High-Throughput Sequencing Technique.

Presentations 2010-2011

DATE PRESENTERS
June 14, 2011 Lucia Martiniova (Stover Lab)
Mouse models to elucidate the mechanisms of foliate-responsive neural tube defects.
Vicki Meyers-Wallen
GWAS in a canine model of XX ovotesticular disorder of sexual development (XX DSD)
May 10, 2011 Patsy Brannon
Regulation of growth of placental trophoblasts by undernutrition and vitamin D
Eric Denkers
Putting Out Fire with Gasoline: What Inbred Mice and a Common Parasite can Tell Us About Inflammatory Bowel Disease in Humans
April 12, 2011 Haibo Sha, CVG Scholar (Qi Lab)
The IRE1a-XBP1 pathway in fat cells
Theodore Clark
Hijacking the regulated secretory pathway of Tetrahymena for production and streamlined purification of recombinant proteins.
March 8, 2011 Martha Stipanuk
The Cysteine Dioxygenase Knockout Mouse -- Metabolic Characterization
Susan Quirk
The hedgehog signaling pathway in ovarian development
February 8, 2011 Cornelia Scheitz (Tumbar Lab)
Of man and mice - Runx1 in squamous cell carcinom
Chang-Il Hwang (Nikitin Lab)
Wild-type p53 controls cell motility and invasion by feedforward loop regulation of MET expression
January 11, 2011 Charles Danko (Siepel Lab)
Variation in RNA Polymerase II Elongation Rate Controls mRNA Concentration
 
December 14, 2010 Lisa Blum (Appleton Lab)
Sounding the alarmin: IL-33 amplifies the immune response to Trichinella spiralis.
Patrick Murphy (Soloway Lab)
Progression Toward Whole Genome Single Molecule High-Through-Put Epigenetic Detection.
November 09, 2010 Mark Roberson
The GnRH signaling network and endocrine control of fertility.
Zhiwu Zhang (Todhunter Lab)
Canine hip dysplasia is predictable by genotyping.
October 12, 2010 Karen Klemnec-Tyburczy
Amphibians, diseases, and declines: Molecular genetics of anuran hosts and fungal pathogen.
Qiaoming Long
Protein Quality Control in the ER and Pancreatic b-cell Functions.
September 14, 2010 Thomas Cleland
Cortical learning in microcosm: the olfactory bulb
Rebecca Tallmadge (Felippe Lab)
Seq'ing answers to CVID

Presentations 2009-2010

DATE PRESENTERS
June 8, 2010 Nathan Clark (Aquadro Lab)
"Mullet: a novel single copy metazoan gene that evolves by extensive insertion/deletion variation and has been the target of strong selection in Drosophila"
Joseph Fetcho
"A ground plan for the organization of the hindbrain."
May 11, 2010 Gregory Acland and Orly Goldstein
"The Continuing Search for Canine Retinal Degeneration Genes"
John Schimenti
"An overview of Cornell's Mammalian Cell Reprogramming Core Facility: from Bioinformatics to iPS cell"
April 13, 2010 Gretchen Mahler (Butcher Lab)
"Inflammation reactivates developmental programming in adult valve cells: Novel mechanisms for valve disease and regeneration"
Samantha Brooks
"Whole Genome SNP Association in the Horse: Identification of a Deletion in Myosin Va Responsible for Lavender Foal Syndrome"
March 9, 2010 Amanda Cass (McCune Lab)
"Of Mice and Fish: conservation and divergence in the expression of key lung morphogenesis genes in the actinopterygian swimbladder"
Jason Gallant (Hopkins Lab)
"Progress in identifying molecular mechanisms of signal evolution in the Mormyrid weakly electric fish"
February 9, 2010 Lindsey Trevino (Johnson Lab)
"Global gene expression analysis in ovarian cancer of the hen"
Irene Min (Lis Lab)
"Genome-wide views of rate-limiting steps in transcription in embryonic stem cells."
January 12, 2010 Chenxi Tian (Liu Lab)
"A conserved RGM family protein DRAG-1 in modulating TGFbeta signaling in C. elegans"
Melanie Craven (Simpson Lab)
"Granulomatous colitis in Boxer dogs"
December 8, 2009 Jennifer Page (Genomics Scholar, Weiss Lab)
"Lethal deregulation of ribonucleotide reductase in transgenic mice"
Xianfei Sun (Genomics Scholar, Cohen Lab)
"Structure -function analysis of mouse MLH3"
November 10, 2009 Benjamin Logsdon (Genomics Scholar, Mezey Lab)
"Reconstructing regulatory networks with random genetic perturbations"
Rodica P. Bunacia (Genomics Scholar, Yen Lab)
"Aryl-Hydrocarbon Receptor and Yamanaka-Thomson Factors in Self-Renewal and Differentiation"
October 6, 2009 Lori McPartlin (Genomics Scholar, Bedford-Guaus Lab)
"The role of the novel cAMP target Epac in stallion sperm capacitation"
Xu Wang (Genomics Scholar, A. Clark Lab)
"Global profiling of allelic imbalance in the mouse"
September 8, 2009 Ashley Woods (Genomics Scholar, Davisson Lab)
"Examining Developmental Defects in a Mouse Model of Pre-Eclampsia, BPH/5
Maria Garcia-Garcia
"Mechanisms underlying axis extension and morphogenesis of extraembryonic tissues in mouse embryos (three years and two mutants later)."

Presentations 2008-2009

DATE PRESENTERS
June 9, 2009 Dr. Tracy Stokol
"Comparative aspects of tissue factor - a key hemostatic protein."
Terri Iwata (S. Lee Lab)
"Investigating HCF proteins as regulators of FOXO and SIRT1 metabolic function."
May 12, 2009 Dr. Nathan Sutter
"The genetics of skeletal size in domestic dogs and horses."
Dr. Ling Qi
"Protein Folding and Inflammation in Obesity and Diabetes"
April 14, 2009 Dr. Dorothy Ainsworth
"What gene expression studies have taught us about equine recurrent airway obstruction."
Dr. Richard Goldstein
"Advances in Feline Genomics"
March 10, 2009 Dr. Elizabeth Buckles
"Host response to acute infection with Infectious Bronchitis Virus."
Dr. Jenifer Cruickshank (Place Lab)
"A putative splice variant of anti-Müllerian hormone receptor missing the transmembrane domain."
February 10, 2009 Dr. Teresa Gunn
"Using mouse genetics to understand the cell biology of spongiform neurodegeneration."
Dr. Marko Vatamaniuk (Lei Lab)
"The mechanisms of hyperinsulinemia in Gpx1 overexpressing mice."
January 13, 2009 Dr. Joy Scaria (YF Chang Lab)
"Analysis of the massive genome variation in Clostridium difficile; a pathogen with unusually low core genome content."
Dr. John Schimenti
Discussion of CVG Funding Priorities
December 9, 2008 Dr. Rui Kan (Coonrod Lab)
"Role for PADI6 and the cytoplasmic lattices in tubulin storage and meiotic spindle assembly in mouse oocyte"
Dr. Kira Novakofski (Fortier Lab)
"Small GTPases in articular chondrocytes"
November 11, 2008 Dr. Kumar Kothapalli (Brenna Lab)
"A partial reexamination of primate polyunsaturated fatty acid biosynthesis by cloning and characterization of baboon fatty acid desaturase (FADS) genes."
Dr. Kevin Harvatine (Boisclair Lab)
"Fatty acid regulation of lipid synthesis: Insights from various mouse lactation models"
October 14, 2008 Dr. John Schimenti
"Genomic etiology of mouse tumors caused by DNA replication deficiency."
Dr. Douglas Antczak
"Horse Genome Project"
September 9, 2008 Mr. Jong Bum Lee (Luo Lab)
"DNA based target-driven polymerization for pathogen detection."
Dr. Watt Webb
"Forthcoming Efficient Deciphering of Vertebrate Genetic Codes."

Presentations 2007-2008

DATE PRESENTERS
June 10, 2008 Dr. David Lin
"One-carbon metabolism and the mouse olfactory system."
Dr. Shelby Dietz (Harris-Warrick Lab)
"Use of transgenic GFP-tagged mice to explore the central pattern generator for locomotion in the mouse spinal cord."
May 13, 2008 Anna Beaudin (Stover Lab)
"Managing Genome Synthesis and Stability: Mechanisms of Folate Responsive Neural Tube Defects"
Dr. Michael Craven (Kotlikoff Lab)
"Characterization of Neonatal Cardiac Precursor Cells from c-kit BAC-EGFP Mice."
April 8, 2008 Dr. Andre Bensadoun
"GPIHBP-1, a novel receptor for chylomicrons, lipoprotein lipase and HDL"
Dr. Anthony Lombardino(DeVoogd Lab)
"Transcription profiling of replaceable neurons from songbirds and mice."
March 11, 2008 Dr. Patsy Brannon
"Maternal malnutrition and regulation of placental growth"
Dr. Shashikant Pujar (Meyers-Wallen Lab)
"Genetic heterogeneity in mammalian sex reversal."
February 12, 2008 Genomics Scholar: Ying Zhang
"Characterization of Stem Cell Proliferation Dynamics in Mouse Hair Follicles"
Dr. Rory Todhunter
"SNPs Predict Susceptibility to Canine Hip Dysplasia"
January 8, 2008 Dr. Anders Lindroth (Paul Soloway Lab)
"DNA and H3K27 methylation are mutually antagonizing epigenetic marks at the imprinted Rasgrf1 locus"
Kevin Harvatine (Dale Bauman Lab)
"Regulation of Milk Fat Synthesis: Nutrigenomics and the Low-Fat Milk Syndrome"
December 11, 2007 Benjamin Logsdon (Dr. Jason Mezey Lab)
"Learning Pathway and Network Structure from Gene Expression and Genotypic Data"
Dr. Eric Denkers
"Adaptive immunity to an intracellular protozoan in the absence of the Toll-like receptor adaptor MyD88"
November 13, 2007 Genomics Scholars:
Ryan Hernandez
"Population Genetic Inference in Primates: The Effect of Context-Dependent Mutation Rates"
Elizabeth Bassity
"Searching for Antigen Presenting Cells in Fish"
October 16, 2007 Genomics Scholars:
Kevin Peterson
"Computational and Experimental Interrogation of the Genomic Regulatory Landscape"
David Corney
"Identification and characterization of miR-34b/c: a p53-dependent microRNA cluster"
September 11, 2007 Dr. Qiaoming Long
"Rfxdc1 is a novel molecular marker for multipotent pancreatic progenitor cells"
Amy Bentley and Susan Wernimont (Dr. Cassano Lab)
"Genomic Approaches to Study Metabolic Networks in Human Populations"

Presentations 2006-2007

DATE PRESENTERS
June 12, 2007 Vimal Selvaraj (Dr. Alex Travis Lab))
"The complexity of sperm membrane domains."
Miltos Kininis (Dr. W. Lee Kraus Lab)
"Genome-wide Analysis of RNA Polymerase II binding and Regulation by Estrogen Signaling."
May 8, 2007 Dr. Gudrun Reiterer (Dr. Andrew Yen Lab)
"The role of the PDGFR during myeloid and monocytic differentitation of HL-60 cells."
Maho Shibata (Dr. Maria Garcia-Garcia Lab)
"Bubbly yolk sacs in a KRAB zinc finger mutant mouse."
April 10, 2007 Dr. Donna Cassidy-Hanley (Dr. Theodore Clark Lab)
"Ich! What are those white spots on my fish? High-throughput sequencing and the search for biological control mechanisms against parasite infection."
Dr. Thomas Cleland
"Triangulating on the olfactory bulb: behavior, circuitry, and genetics."
March 13, 2007 Xia Xu (Genomics Scholar)
"A novel mouse lung cancer model based on overexpression of ribonucleotide reductase."
Li Han (Genomics Scholar)
"The role of Dlx3 in gene regulation in the mouse placenta."
February 13, 2007 Dr. Joseph Fetcho
"You can see into zebrafish and they have genes too."
Dr. Rebecca Holmes (Genomics Scholar)
"Meiosis and the Argonautes"
January 9, 2007 Dr. Ynte Schukken
"Survival of Mycobacterium avium subsp. paratuberculosis in bovine monocyte-derived macrophages from infectious and non-infectious hosts."
Dr. Susan Quirk
"Transgenic models for studying the role of the hedgehog signaling pathway in the mammalian ovary."
December 12, 2006 Dr. Carlos Bustamante
"Statistical and computational methods for enabling association mapping in natural populations and domesticated species."
Dr. Bronislava Brejova (Dr. Adam Siepel Lab)
"Comparative single-exon gene finding."
November 14, 2006 Dr. S Sylvia Lee
"Systematic analysis of longevity determinants in C. elegans"
Mr. John Dominy (Dr. Martha Stipanuk Lab)
"Post-translational regulation of cysteine dioxygenase turnover by intracellular cysteine levels."
September 12, 2006 Dr. Yves Boisclair
"Role of the circulating IGF system in growth and metabolism"
Dr. James P. Camp (Tracy Stokol Lab)
"Engineering better bio research: using tissue engineering methods to make in vitro cultures give physiological results."

Presentations 2005-2006

DATE PRESENTERS
June 13, 2006 Karen Osorio (Dr. Tudorita Tumbar Lab)
"Hair follicle stem cell regulation."
Dr. Teresa Gunn
"Genetic and molecular studies of heart arrhythmias in dogs."
May 9, 2006 Dr. Koodali T. Nishant
"Molecular features of mammalian meiotic recombination hot spots."
Dr. Anders Lindroth (Dr. Paul Soloway Lab)
"Repeat-dependent epigenetic silencing at the imprinted Rasgrf1 locus."
April 11, 2006 Dr. Yung-Fu Chang
"Differentiation of Salmonella enterica serovars by oligonucleotide spotted array."
Dr. David McCobb
"Stress, steroids, and BK channels in adrenals and pituitaries."
March 14, 2006 Dr. Robert Weiss
"Genome maintenance by the Hus1 cell cycle checkpoint protein."
Mr. Scott Valastyan (Dr. Danny Manor Lab)
"Transcriptional activities of vitamin E."
February 14, 2006 Dr. John Schimenti
"Genetic and functional analysis of 1% of the mammalian development-ome."
Dr. Xingen Lei
"Mysterious responses to knockout of two major antioxidant enzymes."
January 10, 2006 Dr. Hong Bo Xin
"Conditional Gene Inactivation in the Mouse: Strategies and Applications."
Mr. Anton Svetlanov (Dr. Paula Cohen Lab)
"DNA Mismatch Repair proteins in mammalian meiosis-recombination, repair, repeats."
December 13, 2005 Dr. Mark Roberson
Cell signaling and the GnRH receptor: membrane compartments, signaling complexes and target genes."
Mr. Kevin Peterson (Dr. Timothy O'Brien Lab)
"Modeling the genomic regulatory network for FGF signaling input to the branching lung epithelium."
November 15, 2005 Dr. J. Thomas Brenna
"Long Chain Polyunsaturated Fatty Acids and Neonatal CNS Development. Non-human Primate Lipidomics and Transcriptomics."
Dr. Richard Goldstein
"Primary Hyperparathyroidism in the Keeshond. A Candidate Gene Approach"
October 11, 2005 Dr. Lisa Fortier
"Determining the role of Cdc42 in osteoarthritis."
Dr. Dan Luo
"Nucleic Acid Engineering: It's Applications in Biotechnology."
September 13, 2005 Dr. Rory Todhunter
"SNP strategy and selection for finer mapping of QTL for canine hip dysplasia."
Dr. Watt Webb
"Animal Genomic Models Help Move Microscopic Imaging Toward Human Medical Diagnostics."

Presentations 2004-2005

DATE PRESENTERS
June 14, 2005 Dr. Timothy DeVoogd
"Using genomic activation as a window into neural processing."
Ms. Maya Grose (Dr. Andre Bensadoun Lab)
"Investigating functions of the heparan sulfate proteoglycan syndecan-4 in lipid metabolism using a knockout mouse model"
May 10, 2005 Dr. Manuel Diaz-Rios (Dr. Harris-Warrick Lab)
"Serotonin modulation of commissural interneuron subtypes in the mouse spinal cord"
Dr. N. Yvonne Tallini (Dr. Kotlikoff Lab)
"Imaging Cellular Calcium in the Embryonic Murine Heart: In Vivo"
April 20, 2005 Mouse Debate
April 12, 2005 Dr. Amanda MacFarlane (Dr. Stover Lab)
"Genome Stability and Methylation in Colon Cancer Initiation"
Mr. Eric Williams (Dr. Lin Lab)
"Screen for axon guidance cues in the mouse olfactory bulb"
March 8, 2005 Dr. Shashikant Pujar (Dr. Meyers-Wallen Lab)
"Canine Sry-negative XX sex reversal: Candidate gene analysis"
Dr. Zongxiang Zhou (Dr. Nikitin Lab)
"Modeling prostate cancer in the mouse"
February 8, 2005 Dr. Bret Payseur (Dr. Andrew Clark Lab)
"Genomic signatures of speciation in inbred strains of mice"
Dr. Kate Whitlock
"Sex, Smells and Videotapes: Development of the Vertebrate Olfactory System"
January 11, 2005 Mr. Miltos Kininis (Dr. W. Lee Kraus Lab)
"Determining Patterns of Factor Recruitment to Estrogen-Regulated Genes on a Global Scale"
Dr. Anna Kukekova (Dr. Greg Acland lab)
"Strategies and applications of genetic mapping in canids"
December 14, 2004 Dr. Thomas Paul (James Casey Laboratory)
"Transgenic expression of walleye dermal sarcoma virus accessory proteins in zebrafish"
Dr. Alexander Travis
"Mice, cats, and dogs: three different models and three different approaches to preserving genetic diversity and creating tools for genomic research"